How Antidiabetic Drug Treatment for Diabetes Works
An antidiabetic drug is a diabetes medication that helps you control your blood glucose. These drugs are also referred to as oral hypoglycemic agents. Most antidiabetic drugs are administered orally with the exceptions of these ones:
A diabetic medication is primarily taken from one of six categories or groups. Your doctor may select your diabetes medication from one of these groups, depending on several factors.
Factors that are considered when selecting an antidiabetic drug
The diabetes medications or drug treatment that your doctor may prescribed for you will depend on a couple of things. They are:
- The nature of your diabetes (type).
- Your age and present situation.
Other factors may also come into play, but the ones above are the main ones.
Categories that describe a particular antidiabetic drug
Depending on the nature of your diabetes illness, your doctor may select the latest diabetes treatment from one of the six groups. These six groups include:
- Insulin . This is the hormone that is responsible for the regulation and control of the glucose in our blood. Insulin is used in diabetes treatment for both type i and type ii diabetes. Most insulin treatments nowadays are manufactured with DNA techniques that are recombinant.
Because of this latest diabetes treatment, it allows for your insulin to be chemically identical to natural human insulin.
- Alpha-glucosidase inhibitors. A diabetic medication from this group does not have any direct effect on your insulin secretion, or its sensitivity. Technically, these anti-diabetic drugs are not considered hypoglycemic agents.
Alpha-glucosidase inhibitors, are prescribed by doctors because they slow down the conversion of disaccharide and complex carbohydrates. This process does not prevent conversion of our foods. Nevertheless - it allows the glucose from our meals to enter into our blood stream more slowly.
It also causes a reduction in the peek levels of our overall blood glucose. A diabetic medication from this group, can be very effective on its own but only in the early stages of impaired glucose tolerance.
Because of this, these diabetes medications are used in combination with other anti-diabetic drugs from one of the other groups.
- Sulfonylureas. These were the first widely used antidiabetic medications in diabetes management. Diabetes medications from this group, treat your illness by causing an increase in the amount of insulin released from the beta cells of our pancreases. A diabetic medication from this group, strongly binds itself to our blood plasma proteins.
These diabetes drugs are only used for type 2 diabetes treatment. Sulfonylureas, according to medical facts, seem to work better in those of us that are over the age of 40 and who have had diabetes for less than 10 years.
These antidiabetic drugs unfortunately, can not be used in the treatment of type 1 diabetics or in women experiencing a diabetes pregnancy. According to diabetic information, the primary side effect of this diabetic drug is hypoglycemia.
- Biguanides. These group of antidiabetic drug medications are used because they cause a reduction in our hepatic glucose output. Subsequently these diabetes drug treatments, will also cause an increase in our peripheral glucose uptake.
There is presently only one member of this group. It is widely used because it apparently does not cause any weight gain. This diabetic medication is called Metformin. Children and teenagers that have type 2 diabetes are normally prescribed metformin as their diabetes treatment.
Biguanides can be used by themselves, or in combinations with an oral anti-diabetic drug from the sulfonylurea group. A word of caution for those of us who are on this particular diabetes drug.
Temporary discontinue your treatment if you are scheduled to under go any type of radiographic procedures, that involves intravenous iodinated contrast. Failure to do so, can increase your risk of developing lactic acidosis.
Meglitinides. There are two diabetic drug medications that make up this group. They are
- Repaglinide (Prandin). These antidiabetic drugs are generally taken 30 minutes before your meals. That is due to the fact that these diabetic medications boost our insulin response for each meal.
If you were to skip a meal, it is highly recommended that you skip your medication as well. The maximum required dosage for this diabetic medication is 16mg per day.
- Nateglinide (Starlix). Recommendation for this particular diabetes treatment is the same as repaglinide but the maximum dosage is different. The dosage is 360mg per day, taken at 120mg increments.
Generally meglitinides can be used alone or in combination with another antidiabetic drug like metformin. Be for warn though, manufacturer of this diabetic drug warns that nateglitinide should never be used along with other antidiabetic drugs that enhance your insulin secretion.
Adverse side effects of this diabetes treatment are weight gain and hypoglycemia.
- Thiazolidinediones. These type of antidiabetic drug medications are also known as "glitazones". Thiazolidinedines diabetic treatment bind themselves to the blood plasma proteins in your body. The blood proteins, also affect the transcription of the genes that regulate the metabolism for our glucose and body fat.
In other words, an antidiabetic drug from this group treat diabetes by causing a reduction in the glucose in your liver. With these particular drugs, your insulin dependent glucose in your muscle cells are increased.
Medications from this group can be used with one from the biguanide group (i.e. metformin) or one from the sulfonylurea group.
When it comes to the dosage of any diabetes medications, they must meet the needs of the patients. Therefore your medication will be based on your blood glucose level, which you eed to checked regularly by the way.
When you are prescribed a diabetes medication, it will be unique to you. Truth be told, as a diabetic patient, make sure that you read the complete dosing information that will accompany your antidiabetic medications.
The information will also direct you on how the drug should be taken, as well as educate you about all the possible side affects. Paying close attention to your diabetes care - will help you avoid serious diabetes complications and get the most out of the antidiabetic drug.
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An antidiabetic drug normally comes in a pill form!
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